Plain pipette tips cleaned by cold plasma and reused up to 50 times, with performance comparable to new. The Novartis and AstraZeneca evaluations, the culture plates and the videos are all on this page.
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A dielectric-barrier discharge turns ordinary room air into reactive species that break down biological and chemical residue on the surface of a tip, plate or pin tool. No solvents, no wash chemistry, about 30 seconds per cycle.
Ordinary room air: nitrogen, oxygen, carbon dioxide and water vapour. Nothing is added.
High voltage across a ceramic barrier ignites a cold plasma at room pressure. One cycle takes about 30 seconds.
Ozone, atomic oxygen and ions decompose DNA, RNA, protein and compound residue at the molecular level.
Plain tips go back into service. Tip integrity is verified through 50 plasma cycles in the Novartis study below.
A single plasma generator supplies the cleaning station on the deck, so one unit serves the whole workcell.
Three station formats cover tip racks in 96 and 384 and pin tools in 1536, on the same generator.
The same discharge cleans inside and outside every tip in a rack, sweeps microplate wells, and strips pin tools.
Eight test conditions. Each image is the culture plate grown from purified water transferred by the tips described, not a photograph of the tips. A red dot means bacterial growth was observed; green means the plate stayed clean. The key result is Plate 8: tips deliberately contaminated with E. coli, washed, then cleaned in the TipCharger. The transfer plate shows no growth, matching brand-new tips.
Drag the slider to compare a brand-new tip against tips cycled 5 to 50 times through the TipCharger. Tip geometry remains intact through 40 cycles, with only minor tip-end wear visible at 50 cycles, which supports reusing each rack for 10 or more runs.
Full lineup, left to right: new tip, then 5, 10, 20, 30, 40 and 50 plasma cycles (Akhlaq et al., Novartis Institutes for BioMedical Research).
Atmospheric plasma is generated in a dielectric-barrier discharge and moved like a fluid, aspirated and dispensed, so it cleans the inside and outside of every tip in the rack and sweeps across microplate wells.
A used plate goes into the MCS DW.
The contact zone travels the tip.
MCS DW treating plates.
TipCharger 384 generator.
Pick the assay you run.
Residual template amplifies exponentially: false positives, contaminated no-template controls, repeat runs.
Plasma destroys DNA, RNA and nucleases rather than diluting them, to PCR-clean levels, in about 30 seconds.
Nuclease carryover has its own white paper; RT-PCR plates were in the AstraZeneca evaluation.
Peer-reviewed papers, NIH NCATS and pharma evaluations, and validation studies. Every card opens the full document. These are independent studies by the named institutions, cited as published evidence and not as endorsements of Augeas Technologies.
Drag the sliders. The model assumes each rack of plain tips is reused for 10 runs (integrity is validated to 50 cycles), 250 operating days a year, the equipment as a one-time purchase, plus a small annual energy and upkeep cost.
Modelled on plain Indian-made racks (about ₹200, Tarsons). Sterile-filter racks cost about ₹442, but we do not model them: filter-barrier integrity after plasma cleaning is not yet published.
Tell us your tip and plate formats and your daily volumes, and we will come back with a modelled saving and a quote.
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